Fosamax (Alendronate Sodium)

Fosamax Review

Fosamax is indicated for treatment and prevention of osteoporosis in postmenopausal women. For the treatment of osteoporosis, Fosamax increases bone mass and reduces the incidence of fractures, including those of the hip and spine. It is also indicated for the prevention of osteoporosis, treatment to increase bone mass in men with osteoporosis, treatment of glucocorticoid. It is used to treat induced osteoporosis in men and women receiving glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and who have low bone mineral density, treatment of Paget's disease of bone in men and women.

Buy Fosamax in a reliable US Online Pharmacy
FedEx Next Day Delivery

Fosamax Drug Class and Mechanism

Alendronate inhibits osteoclast-mediated bone-resorption. Like all bisphosphonates it is chemically related to inorganic pyrophosphate, the endogenous regulator of bone turnover. Whereas pyrophosphate and the first bisphosphonate, etidronate, are capable of inhibiting both osteoclastic bone resorption as well as the mineralization of the bone newly formed by osteoblasts, alendronate and the other potent N-containing bisphosphonates such as risedronate and ibandronate and zoledronate specifically inhibit bone resorption without any effect on mineralization at pharmacalogically achievable doses. Its inhibition of bone-resorption is dose-dependent and approximately 1,000 times stronger than the equimolar effect of etidronate. Under therapy normal bone tissue develops, and alendronate is deposited in the bone-matrix in pharmacologically inactive form. For optimal action enough calcium and vitamin D are needed in the body in order to promote normal bone development. Hypocalcemia should therefore be corrected before starting therapy.

Fosamax Uses

Follow your doctor's instructions strictly. This medication comes in two forms-once a week and once a day. If you take it once a week, take it on the same day each week. Take the medicine first in the morning with a glass of water at least 30 minutes before eating any food or drink. The timing is very important for better results.

Fosamax Side Effects

What side effects might I notice from taking Fosamax? Side effects that you should report to your prescriber or health care professional as soon as possible: More common; stomach pain; heartburn; pain or difficulty swallowing Rare or uncommon:; black or tarry stools; skin rash, itching (hives); swelling of the lips, arms, legs, face, tongue, or throat; vomiting; allergic reactions such as hives, swelling of the face, lips or tongue Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):; diarrhea or constipation; headache; stomach gas or fullness; nausea; changes in taste; bone, muscle or joint pain; rash, which may be made worse by prolonged exposure to sunlight

Fosamax Pregnancy

There are no studies in pregnant women. FOSAMAX should be used during pregnancy only if the potential benefit justifies the potential risk to the mother and fetus.

Fosamax Overdose

No specific information is available on the treatment of overdosage with FOSAMAX. Hypocalcemia, hypophosphatemia, and upper gastrointestinal adverse events, such as upset stomach, heartburn, esophagitis, gastritis, or ulcer, may result from oral overdosage. Milk or antacids should be given to bind alendronate. Due to the risk of esophageal irritation, vomiting should not be induced and the patient should remain fully upright.

Fosamax More Information

Follow you doctor's recommendations about drinking alcohol and smoking. These activities are related to decreased bone density. Antacids and other medicines taken by mouth may decrease the effects of Fosamax. Do not take any other medicines within 30 minutes after a dose of Fosamax. Talk to your doctor before taking any other medicines during treatment with Fosamax